Dr. Marlena Fejzo discusses genetic research on hyperemesis gravidarum (HG). The study focuses on maternal and fetal genes, highlighting GWAS and exome sequencing approaches. In addition to key genes including GDF15 and IGFBP7, new genetic associations are identified with implications for appetite, insulin signaling, and brain function. The evolutionary context of nausea and vomiting is also discussed. The research aims to improve prediction, diagnosis, and treatment of HG through insights into genetic factors contributing to HG.

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The Search for a Cause - Multi-Ethnic Meta-Analysis Identifies New Genes Associated with HG presented by Dr. Marlena Fejzo, PhD at the International Colloquium of Hyperemesis Gravidarum (ICHG) 2024 conference in Ventura, California.